通讯地址:北京市房山区v66体育良乡校区轻工食品大楼A210
联系方式:yunxuex@126.com
教育与研究经历:
2011年-2015年,北京化工大学,生物技术,本科。
2015年-2021年,北京大学,整合生命科学(生物医学工程),博士。
2021年-2025年,北京大学,生物医学工程,博士后。
2025年-至今,v66体育v66体育化妆品系,讲师。
科研项目:
主持国家自然科学基金青年项目(82402460)。
主要研究领域:
(1)基于超声和光学手段的纳米分子影像与肿瘤微创诊疗研究
(2)纳米化妆品技术
(3)超声促进药物/化妆品有效成分的经皮渗透研究
代表性论文:
[1] Xu Y#, Zeng W#, Liu R, et al. Synergistic Nucleus-Targeting Photodynamic Therapy and DNA Repair Inhibition to Activate Innate and Adaptive Antitumor Immunity for Amplifying Photoimmunotherapy[J]. Nano Letters, 2025, 25 (45): 16154-16161.
[2] Yang P#, Xu Y#, Zhi X, et al. Photodynamically Tumor Vessel Destruction Amplified Tumor Targeting of Nanoparticles for Efficient Chemotherapy[J]. ACS Nano, 2024, 18(20): 12933-12944.
[3] Wang B#, Wang W#, Xu Y#, Liu R*, Li R, Yang P. Zhao C. Dai Z, Wang Y, Manipulating Redox Homeostasis of Cancer Stem Cells Overcome Chemotherapeutic Resistance through Photoactivatable Biomimetic Nanodiscs. Small, 2024, 20(28), 2308539.
[4] Liu R*, Yang H, Qu S, Yang P, Zhi X, Xu Y*, Dai Z*, Qian L*. Photodynamic eradication of intratumoral microbiota with bacteria-targeted micelles overcomes gemcitabine resistance of pancreatic cancer. Aggregate, 2023, 00, e423. (共同通讯)
[5] Xu Y, Liu R, Li R, et al. Manipulating Neovasculature-Targeting Capability of Biomimetic Nanodiscs for Synergistic Photoactivatable Tumor Infarction and Chemotherapy[J]. ACS Nano, 2023, 17(16): 16192-16203.
[6] Xu Y#, Liu R#, Yang H, Qu S, Qian L, Dai Z. Enhancing photodynamic therapy efficacy against cancer metastasis by ultrasound-mediated oxygen microbubble destruction to boost tumor-targeted delivery of oxygen and renal-clearable photosensitizer micelles. ACS Applied Materials & Interfaces, 2022, 14 (22): 25197-25208.
[7] Xu Y#, Liu R#, Dai Z. Key considerations in designing CRISPR/Cas9-carrying nanoparticles for therapeutic genome editing. Nanoscale, 2020, 12(24): 21001-21014.
Xu Y#, Liang X#, Bhattarai P, et al. Enhancing therapeutic efficacy of combined cancer phototherapy by ultrasound‐mediated in situ conversion of near‐infrared cyanine/porphyrin microbubbles into nanoparticles. Advanced Functional Materials, 2017, 27(48): 1704096.